Despite is a common preposition. And produces a common error: despite of.
When using despite, there’s no need to attach of.
- He remains a great leader despite age and infirmity. (The New Oxford American Dictionary)
- She ran the race despite an injury. (Merriam-Webster Learner’s Dictionary)
- Despite our best efforts to save him, the patient died during the night.
- They are not getting married, despite rumors to the contrary. [=even though there have been rumors saying they are getting married]
- Despite its small size, the device is able to store thousands of hours of music.
Despite means in spite of (written as three words, not inspite of). I favor conciseness, so I use the shorter despite instead of the longer in spite of.
Photo credit: wired.co.uk